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Symbol
Name
ID
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
MGI:108074
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal thymus morphology
decreased thymus weight
decreased bone marrow cell number
increased erythrocyte cell number
increased hematocrit
increased hemoglobin content
increased neutrophil cell number
increased dendritic cell number
increased T-helper 17 cell number
increased gamma-delta T cell number
decreased lymphocyte cell number
reticulocytopenia
abnormal Langerhans cell morphology
abnormal dendritic epidermal T cell morphology
abnormal spleen morphology
decreased spleen weight
Availability Mouse Genotype
Sptlc2tm1Yhir/Sptlc2tm1Yhir
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+  (conditional)
Sptlc2tm1Yhir/Sptlc2tm1Yhir
Tg(KRT5-cre)1Tak/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory